Doug Manion M.D., FRCP(C)

Doug is CEO of Kleo Pharmaceuticals.  He has 20 years’ experience in drug development.  He was the Senior Vice President, Head of Specialty Development and Head of Japan and China R&D at BMS until October 2016.  He had leadership roles at BMS overseeing various therapeutic areas including virology, immunoscience, neurology, cardiology, metabolic diseases, genetically-defined diseases and fibrosis since joining in 2005. From 2001 to 2005, he was Vice President of Clinical Development and Medical Affairs for HIV/AIDS at GSK. He started his career at DuPont Pharmaceuticals in 1997.  He is Board Certified in Internal Medicine and completed his Fellowship in Infectious Diseases in Ottawa Canada and a clinical and bench research fellowship at Massachusetts General Hospital and Harvard Medical School.  Doug also serves on the Board of Directors of Celleron Therapeutics.

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Luca Rastelli, PH.D.

Dr. Luca Rastelli is the CSO of Kleo. He has more than 20 years of drug discovery and development experience in bio-pharmaceutical companies. He was Vice President for Oncology and Translational Sciences at BioXcel Therapeutics until March 2018. Previously he has held multiple preclinical and clinical project leadership positions at Curagen, Sopherion, EMD Serono and Boston Strategics. He was also involved in the set up and early development of the approved immuno-oncology agent Bavencio (anti-PDL1) and he has discovered the target and led the initial development of Glembatumumab vedotin (CR011 anti-GPNMB). His academic training was focused on how Developmental Biology affects cancerogenesis. For this work, he received the American Brain Tumor Association’s 25th Anniversary Translational grant while at the Department of Neuro-Oncology, MD Anderson Cancer Center.


Roy Prieb

Roy Prieb is the COO/CFO and co-founder of Kleo Pharmaceuticals. He is a technology entrepreneur with over 15 years experience in business strategy, development, and operations. Roy has helped launch, fund, and grow several digital media ventures including Saaspire, Kellogg Media Group,, and Earlier in his career, he was a consultant with The Boston Consulting Group. He received his B.A. from Harvard University and M.B.A. from Wharton Business School.